Tirzepatide
| Dzina lodziwika: | Tirzepatide |
| Cas No.: | 2023788-19-2 |
| Molecular formula: | C225H348N48O68 |
| Kulemera kwa mamolekyu: | 4813.45 g / mol |
| Kutsata: | H-Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-{diacid-gamma-Glu -(AEEA)2-Lys}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| Maonekedwe: | White ufa |
| Ntchito: | Tirzepatide ndi mankhwala omwe amaphunziridwa kuti agwiritsidwe ntchito pochiza matenda a shuga a 2. Ndi m'gulu la mankhwala otchedwa diglucose-dependent insulinotropic peptide (GIP) ndi glucagon-like peptide-1 (GLP-1) receptor agonists. Tezepatide imagwira ntchito polimbikitsa ma GIP ndi GLP-1 receptors m'thupi. Ma receptor awa amatenga gawo lofunikira pakuwongolera kuchuluka kwa shuga m'magazi ndi metabolism. Poyambitsa zolandilira izi, tezepatide imakulitsa kupanga kwa insulin ndikuchepetsa katulutsidwe ka glucagon, timadzi timene timakweza shuga m'magazi. Amachepetsanso kutuluka kwa m'mimba ndipo amathandizira kuwongolera kuchuluka kwa shuga m'magazi. Mayesero azachipatala awonetsa kuti tilsiparatide imatha kuwongolera shuga m'magazi mwa odwala omwe ali ndi matenda amtundu wa 2. Zapezekanso kuti zimalimbikitsa kuchepa kwa thupi, zomwe ndizowonjezera phindu kwa anthu ambiri omwe ali ndi matenda a shuga a mtundu wa 2 omwe amavutika kuti azikhala ndi thanzi labwino. Ubwino umodzi wa tezeparatide ndi mlingo wake womwe umagwiritsidwa ntchito kamodzi pamlungu, womwe ukhoza kuwonjezera kusavuta komanso kutsata dongosolo lamankhwala. Izi zitha kukhala zopindulitsa makamaka kwa anthu omwe amavutika kutsatira dongosolo lamankhwala latsiku ndi tsiku kapena omwe amakonda njira yokhazikika yamankhwala. Tikumbukenso kuti tilsparatide akadali mu siteji kufufuza ndipo sanavomerezedwe ntchito ndi mabungwe olamulira. Kafukufuku wowonjezereka akufunika kuti adziwe chitetezo chake cha nthawi yayitali komanso mphamvu zake komanso kuti adziwe zotsatira zake. Mwachidule, tilsiparatide ndi mankhwala atsopano omwe akufufuzidwa pochiza matenda amtundu wa 2. Kuchita kwake kwapawiri pa GIP ndi GLP-1 receptors kumatha kuwongolera kuwongolera kwa glycemic ndikuchepetsa thupi. Komabe, kafukufuku wochulukirapo amafunika kuti tilsiparatide isavomerezedwe ngati njira yochizira anthu omwe ali ndi matenda amtundu wa 2. |
| Phukusi: | thumba la aluminiyamu zojambulazo kapena aluminium TIN kapena malinga ndi zomwe kasitomala amafuna |
| 1 | Katswiri wothandizira ma peptide API ochokera ku China. |
| 2 | Mizere yopangira 16 yokhala ndi mphamvu zokwanira zopangira zokhala ndi mtengo wampikisano |
| 3 | DMF ikupezeka ndi zolembedwa zodalirika kwambiri. |
A: Inde, tikhoza kunyamula monga kufunikira kwanu.
A: LC kuona ndi TT pasadakhale malipiro nthawi yokonda.
A: Inde, chonde perekani zamtundu wanu, tidzayang'ana ndi R&D yathu ndikuyesera kufananiza mawonekedwe anu apamwamba.
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