Ufa wapamwamba kwambiri wa Cagrilintide API
| Dzina lodziwika: | Cagrilintide |
| Cas No.: | 1415456-99-3 |
| Molecular formula: | Mtengo wa C194H312N54O59S2 |
| Kulemera kwa mamolekyu: | 4109 g / mol |
| Maonekedwe: | White ufa |
| Ntchito: | Cagrilintide ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda amtundu wa 2. Ndi peptide yopanga yomwe imakhala ngati agonist pa glucagon-ngati peptide-1 (GLP-1) receptor. GLP-1 ndi mahomoni opangidwa m'matumbo omwe amathandizira kuwongolera kuchuluka kwa shuga m'magazi. Ma Caglilin peptides amagwira ntchito polimbikitsa cholandilira cha GLP-1, zomwe zimapangitsa kuti katulutsidwe ka insulini kachulukidwe, kuchepa kwa katulutsidwe ka glucagon, komanso kutulutsa pang'onopang'ono m'mimba. Izi pamapeto pake zimathandiza kuwongolera kuchuluka kwa shuga m'magazi mwa anthu omwe ali ndi matenda a shuga a 2. Kuphatikiza pa zotsatira zake pa insulin ndi glucagon secretion, caglilintide ili ndi zotsatira zina zopindulitsa pochiza matenda a shuga a 2. Zapezeka kuti zimalimbikitsa kumverera kwa kukhuta, zomwe zimapangitsa kuchepetsa kudya komanso kuchepa thupi kwa odwala ena. Izi ndizofunikira chifukwa kuchepa thupi kumalumikizidwa ndi kuwongolera bwino kwa glycemic ndikuchepetsa chiopsezo cha zovuta zamtima mwa anthu omwe ali ndi matenda amtundu wa 2. Kuphatikiza apo, mafunde a canagrelin awonetsedwa kuti ali ndi phindu pamtima. Zapezeka kuti zimathandizira kugwira ntchito kwa mtima komanso kuchepetsa kutupa m'mitsempha yamtima, vuto lomwe limapezeka mwa anthu odwala matenda ashuga. Izi zimapangitsa kukhala njira yofunikira kwa odwala matenda ashuga komanso matenda amtima. Canagrelin nthawi zambiri amabayidwa pansi pa khungu kamodzi kapena kawiri tsiku lililonse. Ndikofunika kuti odwala alandire maphunziro oyenerera ndi malangizo a momwe angadzipangire okha mankhwala kuti awonetsetse kuti akugwiritsidwa ntchito moyenera komanso motetezeka. Monga mankhwala aliwonse, caglilintide imakhala ndi zotsatirapo zake. Zotsatira zoyipa kwambiri ndi monga nseru, kusanza komanso kutsekula m'mimba. Zotsatira zoyipazi nthawi zambiri zimasintha pakapita nthawi thupi likamasinthira kumankhwala. Canagrelin imathanso kukulitsa chiwopsezo cha hypoglycemia, makamaka ikagwiritsidwa ntchito limodzi ndi mankhwala ena ochepetsa shuga. Kuwunika pafupipafupi kwa shuga m'magazi ndikofunikira kuti mupewe ndikuwongolera hypoglycemia. Ponseponse, mafunde a caglilin ndiwowonjezera pazosankha zamankhwala kwa odwala omwe ali ndi matenda amtundu wa 2. Zimathandizira kuwongolera kuchuluka kwa shuga m'magazi, zimathandizira kuchepa thupi, komanso zimakhala ndi phindu pamtima. Komabe, ndikofunikira kuti odwala azigwira ntchito limodzi ndi wothandizira zaumoyo wawo kuti adziwe ngati canagrelintide ndi chisankho choyenera kwa iwo ndikuwonetsetsa kuti mankhwalawa akugwiritsidwa ntchito moyenera komanso moyenera. |
| Phukusi: | thumba la aluminiyamu zojambulazo kapena aluminium TIN kapena malinga ndi zomwe kasitomala amafuna |
| 1 | Katswiri wothandizira ma peptide API ochokera ku China. |
| 2 | Mizere yopangira 16 yokhala ndi mphamvu zokwanira zopangira zokhala ndi mtengo wampikisano |
| 3 | Zogulitsa zimapangidwa ku US FDA ndi tsamba lovomerezeka la EDQM. |
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A: LC kuona ndi TT pasadakhale malipiro nthawi yokonda.
A: Inde, chonde perekani zamtundu wanu, tidzayang'ana ndi R&D yathu ndikuyesera kufananiza mawonekedwe anu apamwamba.
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